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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1B
All Species:
13.64
Human Site:
T475
Identified Species:
30
UniProt:
P35368
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35368
NP_000670.1
520
56836
T475
H
D
S
G
P
L
F
T
F
K
L
L
T
E
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
S379
C
A
A
D
R
P
A
S
S
P
R
A
P
L
R
Dog
Lupus familis
XP_536449
618
67286
C481
P
L
G
A
R
R
F
C
P
C
Q
S
R
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P97717
514
56400
T469
L
D
S
G
P
L
F
T
F
K
L
L
G
E
P
Rat
Rattus norvegicus
P15823
515
56567
T470
L
D
S
G
P
L
F
T
F
K
L
L
G
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506393
511
56733
T463
R
D
P
G
H
F
F
T
F
K
F
L
T
E
H
Chicken
Gallus gallus
XP_414483
507
56995
T464
K
D
P
C
Q
F
F
T
F
N
L
L
T
E
R
Frog
Xenopus laevis
O42574
385
43291
D346
L
C
C
P
K
K
A
D
R
H
L
H
T
T
G
Zebra Danio
Brachydanio rerio
XP_001922013
544
60273
F455
Q
A
T
S
P
L
G
F
Y
S
L
V
L
C
Q
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
A384
Y
M
P
E
W
L
G
A
V
I
N
W
L
G
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
H510
E
R
G
H
R
I
Y
H
F
S
S
S
S
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
32.1
76.8
N.A.
94.8
94.6
N.A.
77.6
70.9
28
54
25.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
N.A.
46.7
79.1
N.A.
96.3
96.5
N.A.
82.8
78.8
43.4
64.3
42.6
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
0
13.3
N.A.
86.6
80
N.A.
60
53.3
13.3
20
6.6
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
86.6
86.6
N.A.
60
53.3
13.3
40
13.3
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
10
0
0
19
10
0
0
0
10
0
0
0
% A
% Cys:
10
10
10
10
0
0
0
10
0
10
0
0
0
10
0
% C
% Asp:
0
46
0
10
0
0
0
10
0
0
0
0
0
10
10
% D
% Glu:
10
0
0
10
0
0
0
0
0
0
0
0
0
46
0
% E
% Phe:
0
0
0
0
0
19
55
10
55
0
10
0
0
0
0
% F
% Gly:
0
0
19
37
0
0
19
0
0
0
0
0
19
10
10
% G
% His:
10
0
0
10
10
0
0
10
0
10
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
10
0
0
0
37
0
0
0
0
0
% K
% Leu:
28
10
0
0
0
46
0
0
0
0
55
46
19
19
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
10
0
28
10
37
10
0
0
10
10
0
0
10
0
37
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
10
10
0
0
28
10
0
0
10
0
10
0
10
0
19
% R
% Ser:
0
0
28
10
0
0
0
10
10
19
10
19
10
0
0
% S
% Thr:
0
0
10
0
0
0
0
46
0
0
0
0
37
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _